Non-Invasive Ventilation as a Method of Airway Clearance and Overnight Ventilation for Patients with for Cystic Fibrosis; Systematic Review

Authors

Fahad Bader AlGhounaim, Ammar Adnan Alhaji, Mania Salem Al-Baqawi, Kamal Kamel Alsofyani, Abdullah Mohammed Al-Mutairi

Abstract

Study aim: This review aim to explore the effects of NIV on airway clearance during sleep in individuals with cystic fibrosis.
Method: In this study we adhered to the Preferred reporting items for systematic reviews and meta-analyses (PRISMA) statement. We focused on studies including individuals with CF, regardless of age, who were identified based on clinical criteria, or genetic analysis with any kind of respiratory failure. We included original studies.We searched the literature for publications published up until 2015 using PubMed, Cochrane, MEDLINE, and Embase.
Result: we included four publications in this investigation. Three trials contain 27 participants investigated NIV as a breathing strategy at night. The outcomes of two single-night trials and the final experiment, which lasted six weeks, are presented separately. Two of these research utilized a nasal mask, while one utilizeface mask. In one investigation, NIV was evaluated as an airway clearing method.
Conclusion: In patients with severe cystic fibrosis, noninvasive positive pressure breathing lowers sleep-related hypoxemia and hypercapnia without interfering with sleep. Uncertainty surrounds the long-term advantages and compliance of noninvasive positive pressure breathing.

Keywords

Cystic Fibrosis, Non-Invasive Ventilation, Airway Clearance

Non-Invasive Ventilation as a Method of Airway Clearance and Overnight Ventilation for Patients with for Cystic Fibrosis; Systematic Review. Fahad Bader AlGhounaim, Ammar Adnan Alhaji, Mania Salem Al-Baqawi, Kamal Kamel Alsofyani, Abdullah Mohammed Al-Mutairi. 2017. IJIRCT, Volume 3, Issue 4. Pages 1-8. https://www.ijirct.org/viewPaper.php?paperId=2411034