Liberal versus conservative oxygen therapy's effectiveness and safety in critically ill people; systematic review

Authors

Ali Mohammed Hummedi, Fatimah Mohammed Alzouri, Insherah Abdullah Abu dheeb, EmanMakki Almostafa, Abeer Ahmed ALMuhana, Zahra Ali Hameed Qurish, Noorah Salem Almarry, Maryam Hassan Al Hamada, Aziza Abdullah Alabdullatif, Eman Salman Hussain Alsafwani, Fatimah Mohammed Alhay

Abstract

Background: Adult patients experiencing acute illness are frequently given large doses of supplemental oxygen, yet the validity of the supporting data is questionable. We conducted a thorough analysis comparing the safety and effectiveness of liberal and conservative oxygen treatment for critically ill adults.
Method: Without regard to language, we searched the Cochrane, MEDLINE, and Embase databases from 2011 to 2016 for randomized controlled trials that contrasted the use of liberal and conservation oxygen therapy in critically ill individuals for this systematic review. Database searches were complemented by checking the reference lists of pertinent papers and reviews. PRISMA guidelines were adhered to.
Results and conclusion: This systematic review includes 5 randomized controlled trials that were carried out in Italy, Sweden, France, Australia, New Zealand, and the United Kingdom. Research focused on individuals suffering from traumatic brain damage, cardiac arrest, myocardial infarction, and intensive care unit admission. There is insufficient evidence to justify the regular use of oxygen in individuals who have myocardial infarction and are not suffering from severe hypoxia or cardiogenic shock at the time of presentation. In the pre-hospital context, titrating oxygen administration to SpO2 after cardiac arrest resuscitation was not practical. After arriving at the hospital, titrating oxygen can be an option. Patients with head trauma can have better results if they get normobaric oxygen treatment during the first six hours following the incident.

Keywords

Liberal oxygen therapy, conservative oxygen therapy, effectiveness, safety, critically ill adult

Liberal versus conservative oxygen therapy's effectiveness and safety in critically ill people; systematic review. Ali Mohammed Hummedi, Fatimah Mohammed Alzouri, Insherah Abdullah Abu dheeb, EmanMakki Almostafa, Abeer Ahmed ALMuhana, Zahra Ali Hameed Qurish, Noorah Salem Almarry, Maryam Hassan Al Hamada, Aziza Abdullah Alabdullatif, Eman Salman Hussain Alsafwani, Fatimah Mohammed Alhay. 2016. IJIRCT, Volume 2, Issue 4. Pages 1-8. https://www.ijirct.org/viewPaper.php?paperId=2410020